Small-Animal PET Imaging of Amyloid-Beta Plaques with PiB and Its Multi-Modal Validation in an APP/PS1 Mouse Model of Alzheimers Disease. (2009) Early-Onset and Robust Amyloid Pathology in a New Homozygous Mouse Model of Alzheimer’s Disease. The ARTE10 model was backcrossed to C57BL/6NTac and is 100% congenic. Genetic Background: C57BL/6NTac background. Please note that shipments may contain animals with a larger weight variation. Orders by weight: Taconic cannot accept orders by weight for this model. ![]() At Taconic Biosciences, we have observed limited mortality post-weaning in the breeding colony, with some incidence of a tremor phenotype.
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